Synchronous triple-negative breast cancer, rectal adenocarcinoma, and chemotherapy-induced hepatitis B virus reactivation: a case report and review of the literature
Case report details chemotherapy-related HBV reactivation in a patient with synchronous cancers, highlighting the importance of monitoring liver function.
Key Points
A 55-year-old woman had synchronous triple-negative breast cancer and rectal adenocarcinoma, with BRCA1/BRCA2 mutation.
Chemotherapy was complicated by hepatitis B virus reactivation, leading to significant liver inflammation and treatment changes.
Surgical interventions successfully removed both cancers, and the patient remains disease-free at a 3-year follow-up.
The case emphasizes the need for routine HBV screening and a multidisciplinary approach in cancer management.