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August 2, 2025International Journal of Molecular Medicine

Histone deacetylase 4: A therapeutic target for cardiovascular diseases (Review)

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Authors

XMXiaotong MaRWRan WeiASAnni Song

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Overview

Review shows that histone deacetylase 4 influences cardiovascular disease progression, suggesting new therapeutic strategies.

Key Points

  • Histone deacetylase 4 plays a pivotal role in the development of cardiovascular diseases such as hypertension and atherosclerosis.
  • Studies indicate that HDAC4 regulates critical processes like inflammation, fibrosis, and apoptosis in CVD.
  • The review highlights the potential therapeutic effects of pharmacological agents and exercise on HDAC4 expression.
  • Future research is essential to uncover the molecular mechanisms of HDAC4 in cardiovascular diseases for better treatment strategies.

Cite This Study

Ma et al. (2025) studied this question.

synapsesocial.com/papers/689a0c7be6551bb0af8d0496https://doi.org/10.3892/ijmm.2025.5599
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