Association between inflammatory bowel disease and the risk of liver cancer: a systematic review and meta-analysis

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Meta-analysis reveals increased liver cancer risk in patients with inflammatory bowel disease, highlighting significant disparities by gender.

Inflammatory bowel disease is linked to an increased liver cancer risk with a relative risk of 1.80.
The meta-analysis included nine cohort studies, focusing on 7,305,655 participants.
Female patients with inflammatory bowel disease showed a significantly higher risk of liver cancer at RR = 2.47.
Findings suggest the need for enhanced monitoring in inflammatory bowel disease patients for liver cancer.

Gu et al. (2025) studied this question.

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Meta-analysis reveals increased liver cancer risk in patients with inflammatory bowel disease, highlighting significant disparities by gender.