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August 1, 2025Open Access

The Effects Of Amoxicillin And Metronidazole On Patients With Untreated Stage Iii Grade C Generalized Periodonti-tis: A Prospective Randomized Clinical Trial With 6- And 12-month Follow-ups

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Authors

BSBarbora StenchlákováMBMartin BacinskyMGMarian Grendár

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Overview

Prospective trial shows lower probing depth with antibiotics in stage III grade C periodontitis, suggesting improved outcomes.

Key Points

  • Adjunctive amoxicillin and metronidazole reduced probing depth significantly at 6 months in periodontitis patients.
  • Changes in clinical attachment loss and bleeding on probing did not show significant differences between groups.
  • The study followed 40 patients over 12 months, measuring various periodontal parameters.
  • Further research is needed to explore the long-term effects of antibiotics on clinical attachment loss.

Cite This Study

Stenchláková et al. (2025) studied this question.

synapsesocial.com/papers/689a0c65e6551bb0af8cfb50https://doi.org/10.20944/preprints202507.2434.v1
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