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August 1, 2025Biological and Pharmaceutical BulletinOpen Access

Reactivating Circadian Rhythms as a Therapeutic Strategy: Insights from Basic Research

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Authors

MDMasao Doi

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Overview

Review explores pharmacological strategies to restore circadian rhythms, indicating potential benefits for disorders like obesity and dry eye disease.

Key Points

  • MAIN FINDING: Restoration of circadian rhythms may help reverse diseases associated with circadian disruption.
  • KEY EVIDENCE: Impaired circadian rhythms are linked to disorders including cancer, obesity, and hypertension.
  • APPROACH: The review discusses three pharmacological strategies, including modulation of gene regulatory circuits.
  • SIGNIFICANCE: Insights into circadian biology can lead to new therapeutic strategies for common diseases.

Cite This Study

Masao Doi (2025) studied this question.

synapsesocial.com/papers/689a0c65e6551bb0af8cf8cfhttps://doi.org/10.1248/bpb.b25-00330
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