Systematic review finds intra-arterial fibrinolysis can improve functional outcomes in stroke patients, suggesting its role alongside endovascular thrombectomy.
Key Points
Adjunctive intra-arterial fibrinolysis shows a mild enhancement in excellent functional recovery for stroke patients after endovascular thrombectomy.
Results indicate functional independence at 90 days did not significantly improve with intra-arterial fibrinolysis compared to thrombectomy alone.
Four randomized controlled trials with a total of 1,392 participants were analyzed to assess treatment efficacy and safety in stroke cases.
Study highlights the need for more high-quality trials to optimize intra-arterial fibrinolysis protocols and refine patient selection.