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July 31, 2025Current Issues in Molecular BiologyOpen Access

Atrial Fibrillation in Diabetes: Pathogenesis and Targeted Rhythm Control Strategies

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Authors

KGKonstantinos GrigoriouPKPaschalis KarakasisKPKonstantinos Pamporis

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Overview

This review demonstrates the link between atrial fibrillation and diabetes, highlighting innovative rhythm control strategies for high-risk patients.

Key Points

  • Diabetes and atrial fibrillation have a complex relationship that increases cardiovascular risk and complicates treatment.
  • Conventional rhythm control methods are less effective in diabetes, indicating the need for new, targeted approaches.
  • SGLT2 inhibitors and GLP-1 receptor agonists show potential antiarrhythmic properties by addressing fibrosis and inflammation.
  • Multi-omics strategies are enhancing our understanding of diabetes-associated atrial fibrillation for better individualized management.

Cite This Study

Grigoriou et al. (2025) studied this question.

synapsesocial.com/papers/689a0c5fe6551bb0af8cf6edhttps://doi.org/10.3390/cimb47070559
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Complex interrelationship and therapeutic advances in diabetic patients with atrial fibrillation2025
  2. 2Diabetes Mellitus and Atrial Fibrillation: Mechanistic Insights and Therapeutic Impacts of Glucose-Lowering Drugs2025
  3. 3Metabolic Remodeling and Mitochondrial Stress in Atrial Fibrillation: Mechanisms and Translational Targets2025
  4. 4Type 1 diabetes mellitus and atrial fibrillation – clinical relationships, mechanistic insights and therapeutic implications2025
  5. 5Metformin as an Upstream Substrate-Modifying Strategy for Atrial Fibrillation in Metabolic Dysfunction: Mechanistic Rationale and Clinical Evidence2026