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July 31, 2025Frontiers in Public HealthOpen Access

The impact of depression on mortality among older adult patients with hypertension: a systematic review and meta-analysis

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Authors

ZFZe FangTHTao HuangQZQiongfang Zhang

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Overview

Systematic review reveals increased mortality risk in older adults with hypertension and depression, suggesting urgent screening needs.

Key Points

  • Depression is linked to increased all-cause mortality in older adults with hypertension, with a hazard ratio of 1.32.
  • Female participants experienced a stronger association, with a hazard ratio of 1.57 for mortality linked to depression.
  • The systematic review included 13 studies with over 483,000 participants and comprehensive mortality assessments.
  • Routine screening and treatment for depression in older adult hypertensive patients may improve health outcomes.

Cite This Study

Fang et al. (2025) studied this question.

synapsesocial.com/papers/689a0c5fe6551bb0af8cf5abhttps://doi.org/10.3389/fpubh.2025.1603785
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