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July 31, 2025Signal Transduction and Targeted TherapyOpen Access

Immune evasion in cancer: mechanisms and cutting-edge therapeutic approaches

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Authors

MTMuhammad TufailCJCanhua JiangNLNing Li

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Overview

This review reveals mechanisms of immune evasion in cancer, emphasizing tumor microenvironment and immunotherapy strategies.

Key Points

  • Immune evasion complicates therapeutic interventions in cancer, leading to poor patient outcomes.
  • Tumors utilize strategies like immune checkpoint regulation and immune suppression to escape immune detection.
  • The tumor microenvironment plays a key role in fostering immune resistance and impacts treatment efficacy.
  • Innovative therapeutic approaches like bispecific antibodies and nanotechnology aim to enhance immunotherapy effectiveness.

Cite This Study

Tufail et al. (2025) studied this question.

synapsesocial.com/papers/689a094be6551bb0af8cf18dhttps://doi.org/10.1038/s41392-025-02280-1
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