Systematic review reveals zinc supplementation reduces emotional and physical premenstrual symptoms in women, suggesting potential as a non-drug intervention.
Key Points
Zinc supplementation effectively reduced total PMS scores with moderate certainty, indicating potential benefits for women.
Meta-analysis showed significant reductions in emotional symptoms (Hedges's g = -0.347) and physical symptoms (g = -0.512).
The review included five randomized controlled trials, with varying levels of risk for bias affecting the findings.
Generalizability is limited by the small number of trials, highlighting the need for further multicenter studies to confirm results.