Paeoniflorin: A Review of its Hepatointestinal Protective Effects and Molecular Mechanisms

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This review highlights paeoniflorin's protective impact on liver and intestinal diseases, indicating its potential in therapy.

Paeoniflorin shows significant anti-inflammatory and antioxidant effects in liver diseases.
The terpenoid glycoside regulates multiple signaling pathways crucial for hepatointestinal health.
PF contributes to liver-intestinal axis interaction, influencing gut health via bile acids.
Enhanced understanding of PF's mechanisms could lead to innovative treatments for hepatointestinal conditions.

Chen et al. (2025) studied this question.

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