July 23, 2025

lncRNAs and miRNAs : key regulators in the pathogenesis of cSCC, senescence, and psoriasis

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lncRNAs and miRNAs are crucial for maintaining skin homeostasis and regulating conditions like cSCC and psoriasis.
Evidence shows that miR-23b acts as a tumor suppressor in cSCC by regulating oncogenic pathways and cell proliferation.
Functional studies confirm that CYDAER impacts keratinocyte differentiation and contributes to the pathology of psoriasis.
miR-383 regulates DNA damage response and fibroblast senescence, highlighting its role in skin aging processes.

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Findings reveal lncRNAs and miRNAs as key regulators of cSCC, psoriasis, and cellular senescence, suggesting potential therapeutic targets.

Jonathan Elton (2025) studied this question.

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Findings reveal lncRNAs and miRNAs as key regulators of cSCC, psoriasis, and cellular senescence, suggesting potential therapeutic targets.