July 23, 2025Frontiers in ImmunologyOpen Access

Innovative microbial strategies in atopic dermatitis

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Review highlights novel microbiome manipulation techniques to improve inflammation in atopic dermatitis, suggesting promising therapeutic approaches.

Innovative microbiome manipulation strategies show promise for managing atopic dermatitis (AD) with fewer side effects.
Dysbiosis and immune imbalance, especially Th2 skewing, are key factors driving atopic dermatitis symptoms.
Various approaches like probiotics and fecal microbiota transplantation are under exploration for mild-to-moderate and refractory AD cases.
Future translational research is crucial to optimize the application of microbiome-based interventions in AD treatment.

Ma et al. (2025) studied this question.

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Review highlights novel microbiome manipulation techniques to improve inflammation in atopic dermatitis, suggesting promising therapeutic approaches.