A Review of the Pharmacological Activities and Safety of Heliotropium indicum

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Scoping review summarizes pharmacological activities and safety concerns of Heliotropium indicum, highlighting adverse effects.

Heliotropium indicum shows a range of pharmacological activities, indicating its potential as a source of bioactive substances.
Nineteen studies analyzed revealed significant anti-inflammatory and antitumor effects alongside safety concerns.
Safety studies indicated adverse effects in animals, including brain abnormalities and liver damage due to toxic alkaloids.
Caution is necessary due to the presence of the toxic compound indicine N-oxide, which caused mortality in animal testing.

Wumbornyi et al. (2025) studied this question.

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