July 23, 2025European Journal of PainOpen Access

Differential Effects of Repetitive Transcranial Magnetic Stimulation on Mood and Pain Symptoms in People With Chronic Pain and Major Depressive Disorders—A Review

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rTMS has distinct effects on mood and pain, with motor cortex stimulation improving pain symptoms.
Dorsolateral prefrontal cortex stimulation alleviates depressive symptoms, but pain relief is inconsistent.
The review included 36 studies using rTMS for fibromyalgia and MDD, focusing on different symptom clusters.
Personalized approaches in rTMS therapy could enhance treatment for chronic pain and mental health disorders.

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Implication

Review finds rTMS provides symptom-specific improvements in chronic pain and major depressive disorder, suggesting the need for personalized treatment strategies.

Cite This Study

Andrade et al. (2025) studied this question.

synapsesocial.com/papers/689a061be6551bb0af8cdadd https://doi.org/10.1002/ejp.70077

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Implication

Review finds rTMS provides symptom-specific improvements in chronic pain and major depressive disorder, suggesting the need for personalized treatment strategies.

Differential Effects of Repetitive Transcranial Magnetic Stimulation on Mood and Pain Symptoms in People With Chronic Pain and Major Depressive Disorders—A Review

Key Points

Discussion

Implication

Cite This Study

Differential Effects of Repetitive Transcranial Magnetic Stimulation on Mood and Pain Symptoms in People With Chronic Pain and Major Depressive Disorders—A Review

Key Points

Discussion

Implication

Cite This Study

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