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July 22, 2025MedCommOpen Access

Extracellular Matrix Signaling Cues: Biological Functions, Diseases, and Therapeutic Targets

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Authors

TZTian ZhaoYHYe HuangJZJingfei Zhu

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Overview

Review uncovers therapeutic targets in extracellular matrix signaling, highlighting its role in diseases like cancer and fibrosis.

Key Points

  • Extracellular matrix (ECM) regulates crucial biological processes, impacting health and disease.
  • Dysregulation of ECM contributes to diseases such as cancer, fibrosis, and cardiovascular disorders.
  • The review identifies integrins and other sensors involved in mechanotransduction affecting cell behavior.
  • Future research aims to integrate ECM-targeted therapies into precision medicine for improved outcomes.

Cite This Study

Zhao et al. (2025) studied this question.

synapsesocial.com/papers/689a061be6551bb0af8cd8adhttps://doi.org/10.1002/mco2.70281
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