Walking on the tightrope: the shared roles of the bridging pericytes in the brain

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Bridging pericytes play essential roles in maintaining blood-CNS barriers and regulating vascular responses.
These structures are involved in neurovascular coupling and may indicate varying vascular conditions.
Pericyte processes can detach to form bridges between capillaries, sparking ongoing debates in research.
Understanding the roles of pericytes in vascular aging could have significant implications for CNS health.

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This review discusses pericytes' roles in blood-CNS barriers and neurovascular coupling, suggesting future research directions.

Chagnot et al. (2025) studied this question.

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