Acquired hemophilia A: a case report and review of the literature

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Discussion

Case report highlights challenges of managing acquired hemophilia A in a 74-year-old patient, suggesting early diagnosis is vital.

MAIN FINDING: Acquired hemophilia A is a rare autoimmune disease linked with significant bleeding risks.
KEY EVIDENCE: Confirmed diagnosis was indicated by hematological tests showing low factor VIII activity at 2.4%.
APPROACH: The patient underwent treatment with hemostatic agents and corticosteroids, leading to improvement of symptoms.
SIGNIFICANCE: Early diagnosis and a personalized management approach can improve outcomes in patients with coagulopathy.

Perotti-Abad et al. (2025) studied this question.

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