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July 21, 2025Cell ProliferationOpen Access

CRISPR Technology in Disease Management: An Updated Review of Clinical Translation and Therapeutic Potential

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Authors

BFBahareh Farasati FarMAMarziyeh AkbariMHMohammad Amin Habibi

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Overview

Review highlights CRISPR's therapeutic potential across oncology, genetic, and neurological disorders, suggesting innovative clinical applications.

Key Points

  • CRISPR-Cas9 enables precise genetic modifications for various diseases, advancing therapeutic opportunities significantly.
  • Recent clinical trials show promising results for CRISPR therapies in hematologic malignancies and solid tumors.
  • CRISPR is being utilized to model and potentially treat neurological disorders like Alzheimer's and ALS.
  • Rapid CRISPR-based diagnostics, such as SHERLOCK, improve pathogen detection, critical during outbreaks like SARS-CoV-2.

Cite This Study

Far et al. (2025) studied this question.

synapsesocial.com/papers/689a060ee6551bb0af8cd19fhttps://doi.org/10.1111/cpr.70099
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Also Consider

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  1. 1CRISPR-Cas9 PROTEIN: PHARMACEUTICAL FRONTIERS IN GENETIC RESTORATION2025
  2. 2Challenges and Opportunities in the Application of CRISPR-Cas9: A Review on Genomic Editing and Therapeutic Potentials2025 · 27 citations
  3. 3CRISPR-Cas9 in Pharmaceutical Research: Applications, Challenges, Ethical Considerations and Future Directions2025 · 7 citations
  4. 4Expanding the CRISPR/Cas toolkit: applications in proteomics and theranostics2025 · 1 citations
  5. 5Recent applications, future perspectives, and limitations of the CRISPR-Cas system2025 · 31 citations