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July 20, 2025JMIR Public Health and SurveillanceOpen Access

Symptom Trajectories and Clinical Subtypes in Post–COVID-19 Condition: Systematic Review and Clustering Analysis

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Authors

MHMingzhi HuTSTian SongZGZhaoyuan Gong

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Overview

Systematic review reveals symptom clusters and clinical subtypes in post–COVID-19 condition, suggesting effective management strategies.

Key Points

  • MAIN FINDING: Core symptoms of post–COVID-19 condition evolve from early respiratory issues to persistent neurological symptoms.
  • KEY EVIDENCE: Fatigue was the most prevalent symptom, affecting about 52% of patients across multiple follow-ups.
  • APPROACH: A meta-analysis of 155 studies involving 63,771 patients was conducted to identify symptom patterns and clinical subtypes.
  • SIGNIFICANCE: Understanding symptom trajectories will enhance management strategies and improve quality of life for patients.

Cite This Study

Hu et al. (2025) studied this question.

synapsesocial.com/papers/689a02c9e6551bb0af8ccf9ehttps://doi.org/10.2196/72221
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