July 19, 2025npj Digital MedicineOpen Access

Large language model integrations in cancer decision-making: a systematic review and meta-analysis

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Systematic review reveals that large language models can improve decision-making in cancer care, highlighting accuracy concerns.

Large language models are being integrated into oncology decision-making to support patients and clinicians.
The meta-analysis included 56 studies across 15 cancer types, showing varied performance and an overall accuracy of 76.2%.
Most studies focused on quantitative evaluations, emphasizing accuracy while neglecting safety and clarity evaluations.
Current limitations of large language models in cancer care highlight the need for better datasets and standardized assessments.

Hao et al. (2025) studied this question.

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