Genome-wide cnv analysis discovers novel loci in schizophrenia and dose-dependent gene effects on psychiatric conditions, indicating complex relationships.
Key Points
Core finding shows 35 genome-wide significant associations at 18 loci related to psychiatric conditions.
Identified novel associations particularly in schizophrenia and across multiple disorders during analysis.
Study involved 574,965 participants across six diagnostic categories using genome-wide cnv analysis.
Findings highlight the pleiotropic effects of genes, indicating both positive and negative influences on psychopathology.