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July 16, 2025Current Issues in Molecular BiologyOpen Access

A Novel Hypoxia-Immune Signature for Gastric Cancer Prognosis and Immunotherapy: Insights from Bulk and Single-Cell RNA-Seq

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Authors

MNMai H. NguyenHTHoang Dang Khoa TaDNDoan Phuong Quy Nguyen

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Overview

Cox regression identifies hypoxia-immune signature influencing prognosis in gastric cancer, suggesting immunotherapy strategies.

Key Points

  • The study identifies a hypoxia-immune gene signature predictive of prognosis in gastric cancer.
  • Five key genes were associated with patient survival and immune response to treatment.
  • Transcriptomic data analysis used Cox regression and validation on multiple datasets for accuracy.
  • The findings may guide treatment strategies and improve outcomes for gastric cancer patients.

Cite This Study

Nguyen et al. (2025) studied this question.

synapsesocial.com/papers/689a02c3e6551bb0af8cccbehttps://doi.org/10.3390/cimb47070552
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