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July 16, 2025HealthcareOpen Access

The Adjunctive Role of Antimicrobial Photodynamic Therapy to Non-Surgical Treatment in Patients with Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis

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Authors

APAlessia PardoASAnnarita SignorielloEMElena Messina

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Overview

Systematic review highlights improved clinical outcomes in T2DM patients undergoing adjunctive antimicrobial photodynamic therapy during non-surgical treatment.

Key Points

  • Adjunctive antimicrobial photodynamic therapy significantly reduces bleeding on probing in T2DM patients after treatment.
  • Probing pocket depth improved substantially in T2DM patients receiving combined therapy compared to NSPT alone.
  • Meta-analysis included 15 studies assessing the efficacy of aPDT alongside typical periodontal treatment.
  • This combined therapy offers a promising approach for managing periodontitis in individuals with type 2 diabetes mellitus.

Cite This Study

Pardo et al. (2025) studied this question.

synapsesocial.com/papers/689a02c3e6551bb0af8cc9abhttps://doi.org/10.3390/healthcare13141703
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Microbiological Impact of Antimicrobial Photodynamic Therapy in Non-Surgical Periodontal Treatment2025
  2. 2Prevention and treatment of periodontal diseases in patients with type 2 diabetes (literature review)2025
  3. 3Use of photosensitizers in photodynamic therapy combined with scaling and root planing for the treatment of periodontitis: a systematic and qualitative review2025
  4. 4Efficacy of photodynamic therapy with various photosensitizers for peri-implantitis treatment: a systematic review and meta-analysis of randomized clinical trials2025
  5. 5Effect of melatonin as an adjunct to non-surgical periodontal therapy in the treatment of periodontitis: A systematic review and meta-analysis2025