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July 15, 2025Open Access

A scoping review of the application of artificial intelligence for the analysis of adverse drug events in clinical research

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Authors

OSOren SchreierAYAnthony YazdaniIGIoannis Galdadas

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Overview

This review identifies 81 studies on artificial intelligence for adverse drug events, indicating promising but challenging applications in clinical research.

Key Points

  • AI is being used to predict and detect adverse drug events during drug development and post-market phases.
  • The review covers 81 articles, focusing on AI methodologies like machine learning and their applications in clinical research.
  • Challenges include data heterogeneity and lack of external validation, affecting model adoption in practice.
  • Despite challenges, AI-based detection can enhance drug safety in both pre- and post-approval phases.

Cite This Study

Schreier et al. (2025) studied this question.

synapsesocial.com/papers/689a02bce6551bb0af8cc930https://doi.org/10.1101/2025.07.14.25331486
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