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July 15, 2025Open Access

Changes in Autonomic Balance, Cardiac Parasympathetic Modulation, and Cardiac Baroreflex Gain in Older Adults Under Different Orthostatic Stress Conditions

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Authors

DMDihogo Gama de MatosJSJefferson Lima de SantanaFAFelipe J. Aidar

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Overview

Study reveals impaired cardiac parasympathetic modulation and diminished autonomic balance under orthostatic stress in older adults, highlighting risks of orthostatic intolerance.

Key Points

  • Older adults show altered autonomic balance and reduced heart rate variability compared to younger adults.
  • During orthostatic stress, older adults exhibited higher cardiac parasympathetic modulation and lower cardiac baroreflex gain.
  • Participants performed sit-to-stand and lie-to-stand maneuvers while monitoring heart rate and blood pressure.
  • Higher incidence of orthostatic intolerance symptoms was reported in older adults compared to younger adults.

Cite This Study

Matos et al. (2025) studied this question.

synapsesocial.com/papers/689a02b6e6551bb0af8cc50bhttps://doi.org/10.20944/preprints202507.1123.v1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Short-Term Cardiovascular Compensatory Responses to Varying Levels of or-Thostatic Stress During Active Standing in Older Adults2025
  2. 2Heart Rate Dynamics During Localized Upper-Extremity Function as a Novel Measure of Cardiac Autonomic Dysfunction: Investigation of Aging- and Disease-Related Alterations2025
  3. 3Pilot study of autonomic and cardiovascular responses to orthostatic stress among young adults with visual and hearing impairments2026
  4. 4Age, Sex, and Central Adiposity as Determinants of Autonomic Nervous System Reactivity in Adults2025
  5. 5Cardiac-neurovascular crosstalk: Cardiac rhythms reveal maladaptive cerebral autoregulation and constrained ventilatory status2025