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July 15, 2025Open Access

Building Trust for Improving Vaccine Uptake: An Integrative Review of COVID-19 Vaccine Hesitancy in the Global North and South

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Authors

FNFatou NdoyeMAMohamed AneMLMarjan Leneman

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Overview

Integrative review reveals psychological and social factors affect vaccine uptake globally, indicating need for targeted public health strategies.

Key Points

  • Vaccine hesitancy is a notable global challenge affecting both the Global North and South.
  • Distrust in pharmaceutical companies and government agencies largely drives vaccine hesitancy.
  • Psychological and social predictors of vaccine refusal are often overlooked but crucial for understanding hesitancy.
  • The proposed conceptual model aims to guide policymakers in addressing vaccine compliance through trust-building.

Cite This Study

Ndoye et al. (2025) studied this question.

synapsesocial.com/papers/689a02b6e6551bb0af8cc4echttps://doi.org/10.20944/preprints202507.1146.v1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Vaccine Hesitancy in Public Healthcare During Pandemics: An International Study to Inform Management Learning2025
  2. 2Identification of Community Vaccine Hesitancy: A Descriptive-Cross-Sectional Study.2025
  3. 3Public COVID-19 vaccination acceptance: A narrative review of correlated factors2022
  4. 4The Impact of National Context on COVID-19 Vaccine Hesitancy Across Europe: A Multi-Level Approach2025
  5. 5Understanding vaccine hesitancy through the lens of trust and the 3C model: evidence from Chinese General Social Survey 20212025