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July 14, 2025European journal of medical researchOpen Access

Pathological mechanisms and treatment progression of Alzheimer’s disease

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Authors

JZJingjing ZhangGKGwyneth KongJYJinyue Yang

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Overview

Comprehensive review uncovers therapeutic challenges and biomarker advancements in Alzheimer’s disease, highlighting personalized medicine strategies.

Key Points

  • Alzheimer's disease is the leading cause of dementia, characterized by amyloid-β plaques and tau tangles.
  • Current treatments like anti-amyloid therapies show limited effectiveness and highlight the need for new strategies.
  • Recent advances include novel biomarkers for early detection and personalized approaches to combat disease heterogeneity.
  • Multimodal interventions targeting various pathological processes offer promise for more effective treatments against Alzheimer's disease.

Cite This Study

Zhang et al. (2025) studied this question.

synapsesocial.com/papers/689a02b6e6551bb0af8cc301https://doi.org/10.1186/s40001-025-02886-9
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