July 14, 2025BMC Women s HealthOpen Access

Effects of letrozole combined with clomiphene in the treatment of polycystic ovary syndrome: a meta-analysis

View Full Paper

Ask AI

Bookmark

Authors

Discussion

Meta-analysis reveals letrozole combined with clomiphene improves pregnancy rates in PCOS patients, suggesting enhanced ovulation induction methods.

Letrozole combined with clomiphene significantly improves pregnancy rates (RR = 1.50, P < 0.00001) in PCOS patients.
Analysis involving 931 PCOS patients showed letrozole and clomiphene also enhanced ovulation rates (RR = 1.29, P < 0.0001).
The study utilized data from RCTs and employed comprehensive statistical analysis with Review Manager and Stata software.
Findings support the use of letrozole and clomiphene as an effective treatment option for ovulatory dysfunction in PCOS.

Du et al. (2025) studied this question.

View Full Paper

Ask AI

Bookmark

Meta-analysis reveals letrozole combined with clomiphene improves pregnancy rates in PCOS patients, suggesting enhanced ovulation induction methods.