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July 12, 2025European Archives of Oto-Rhino-LaryngologyOpen Access

Efficacy and safety of radiofrequency ablation (RFA) for recurrent metastatic thyroid carcinoma to the lateral neck: a systematic review

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Authors

CGCarlos GalanDKDevanshu KwatraAVAnanth Vijendren

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Overview

Systematic review shows RFA for lateral neck recurrence improves safety and efficacy compared to surgery, suggesting it as a viable alternative.

Key Points

  • RFA achieved up to 97% complete nodule disappearance among 252 patients, indicating high efficacy for metastatic thyroid carcinoma.
  • Volume reduction rates with RFA reached 93–100% over 24–60 months, showcasing its effectiveness against locoregional recurrence.
  • Complications were lower with RFA compared to surgery, which had higher rates of hypocalcemia (8.7–30%) and voice changes.
  • Thyroglobulin levels decreased significantly post-RFA, suggesting its potential for effective disease management and monitoring.

Cite This Study

Galan et al. (2025) studied this question.

synapsesocial.com/papers/689a02afe6551bb0af8cbf38https://doi.org/10.1007/s00405-025-09563-x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Preliminary results of a prospective study on the efficacy and safety of single-session radiofrequency ablation in treating benign thyroid nodules2025
  2. 2Efficiency of Radiofrequency Ablation in Treatment of Thyroid Nodules in Iraqi Patients with Nodular Goiter2025
  3. 3A Systematic Review And Meta-Analysis Comparing The Prognoses Of Benign Thyroid Nodules Using Radiofrequency Ablation Versus Lobectomy2025
  4. 4Thermal Ablation vs. Conventional Neck Dissection for Recurrent Low-Burden Lymph Node Metastasis in Thyroid Cancer: A Dual-Center Retrospective Cohort Study2025
  5. 5Predictors of Suboptimal Response After Radiofrequency Ablation of Benign Thyroid Nodules2025