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August 7, 2025International Journal of Molecular SciencesOpen Access

Association of miRNA-17-92 Cluster with Muscle Invasion in Bladder Cancer

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Authors

MPMihai PăvăleanMDMaria DobreIPIulia Andreea Pelisenco

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Overview

Evaluation shows miRNA-17-92 correlates with muscle invasion in bladder cancer patients, suggesting new markers for aggressiveness.

Key Points

  • The study identifies a link between the miRNA-17-92 cluster and muscle invasion in bladder cancer.
  • miR-17-5p, miR-18a-5p, miR-19a-3p, and miR-20a-5p were found to be upregulated in tumor tissues.
  • A total of 84 miRNAs were analyzed using qRT-PCR to explore their relationship with tumor characteristics.
  • Discovering these dysregulated miRNAs may improve disease monitoring and treatment strategies for bladder cancer.

Cite This Study

Păvălean et al. (2025) studied this question.

synapsesocial.com/papers/689522189f4f1c896c429c2dhttps://doi.org/10.3390/ijms26157546
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